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Metabolism Function of Uric Acid: Link to Cognitive Impairment

By travels, published Jan 27, 2007
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Uric acid (From foods eaten) is made in the liver and is excreted by the kidneys (Passes out of the body in urine). It is an organic compound of carbon, nitrogen, oxygen and hydrogen. Uric acid is the end product that metabolizes or physical and chemical process, within the body create and use energy (Breathing, circulating blood, digesting food and nutrients, eliminating waste through urine and feces, and regulating temperature). When uric acid concentrates (not able to be pass through the urine) or consequently lower than normal levels in the kidney, develop serious medical health concerns. A uric acid blood test or urine test evaluates the amount of uric acid in the body, (Normal values fall between: Male - 2.1 - 8.5 mg/dL and Female: 2.0 - 6.6 mg/dL. Slightly higher range in the elderly.).

Recommended four hours before the test (preferable 24 hours) discontinue taking any drugs, alcohol, aspirin, caffeine or any substances, which may adversely affect the result of the test. Increase concentration of uric acid can cause crystals to form in the joints, which leads to join inflammation and pain characteristic of gout. Also, crystals can form stones in the kidneys, which can damage the organ. Other related medical problems arising from high uric acid includes: Diabetes, lead poisoning, renal failure (loss ability of the kidneys to remove waste and concentrate urine), Hypoparathyroidsm (A condition in which the body produces too little parathyroid hormone, important to regulate calcium and phosphorus in bone and blood), preclampsia (After twentieth week of pregnancy, elevated blood pressure and protein in the urine, may result in premature delivery.), Leukemia, and cardiovascular disease.

Takeaways
  • Increase level of Uric acid leads to join inflammation and pain characteristic of gout.
  • Lower than normal levels of Uric acid may indicate: Wilson Disease, Fanconi's syndrome and Multiple Sclerosis.
  • Uric acid level increase with age, although the reason behind it is not entirely clear.
Did You Know?
Uric acid known to have antioxidant properties.
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