Justifications for the Amino Acid Theory of Schizophrenia

Introduction

I have been touting the amino acid theory of schizophrenia. I feel that the same theory is valid for depression and other psychiatric diagnoses. Since amino acids are in the diet, this points towards an alternative medicine treatment for psychiatric diseases. In other words, these diseases are food allergies.

Orlovskaya et al (1975)

These Russian scientists studied the brain cells of embryos from schizophrenic Mothers. They found "granular inclusions" in the cytoplasm. Some inclusions were associated with the endoplasmic reticulum.

They concluded that there was a toxic factor that detroys the integrity of the plasma membrane (also called the cell membrane). The mitochondria showed swelling, clarification of the matrix, and destruction of cristae. The "clarification" of the matrix could mean that fat was being produced and deposited in the matrix.

Similar results on other test objects were reported by Solov'eva et al (1970), by Savulev (1967), and by Tikhonov et al (1967).

The synthesis apparatus was affected. This apparatus houses amino acids. This suggests a possible error in amino acid metabolism or amino acid transport.

Macht (1949)

Macht of the UK reported a toxic factor which inhibited plant growth.

Reider (1957)

Reider of the US used a spider web assay to detect a toxic factor in the blood serum of schizophrenics.

Lidemann (1965)

Lidemann used blood cells as an assay. Hemolysis was caused by the toxic blood factor.

Nishimura eta al (2000)

This Japanese group reported carbohydrate deposits in "the molecular layer of the dentate gyrus in the hippocampal formation of patients with schizophrenia". This strongly suggests flawed glucose metabolism. The glucose metabolism is probably slow.

The Vogts