Problems Posed by Antibiotic-Resistant Tuberculosis Bacteria

How Evolution Complicates the Fight Against Infectious Disease

By G. Stolyarov II, published May 30, 2007
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Tuberculosis (TB) has been successfully fought with antibiotics for decades, but the emergence of antibiotic-resistance TB bacteria has resulted in numerous complications in the battle against this disease.

Misuse of antibiotics via their frequent introduction into an individual's body may destroy certain weaker strains of the TB bacteria, but will leave in place the few bacteria that have by chance been born with the ability to resist the antibiotics used. These bacteria will then have no obstacle toward proliferating and thus contributing to the evolution of a strain almost fully resistant to that particular antibiotic. The resistant bacteria are naturally selected to survive and multiply as the fittest under such conditions.

When an environment rich in bacteria for a particular disease exists, it may be possible for several afflicted persons to be treated with a different antibiotic each and for those persons to develop strains of bacteria immune to that particular antibiotic. Due to frequent contact between these individuals, the various specifically immune strains can transfer from one individual to another. Within a given individual's body a strain immune to antibiotic A is free to undergo genetic recombination with a strain immune to antibiotic B, thus sometimes transferring immunity to two or more antibiotics to a given set of bacterial organisms, whose multiplication can bring about a populous multi-resistant strain.

Did You Know?
The TB bacteria, often latent in healthy individuals, more frequently manifests itself in the malnourished prisoners, many of whom additionally undermine their health via alcoholism.
Comments
Showing Comments 1 - 3 of 3
 
 
Well thought out and personally not so sure that breeding the resistant ones for study is really so wise. Time will tell. Thank you for a fine article.

Posted on 12/09/2007 at 8:12:00 AM

 
great article :-)

Posted on 06/01/2007 at 7:06:00 AM

 
Antibiotic resistant are two very scary words when put together. Great article. I hadn't heard the information about the Russian prison system.

Posted on 05/31/2007 at 1:05:00 PM

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