Side Effects of the Medical Steroid, Prednisone

Life Long Benefit and Life Long Effects

The glucocorticosteroid, prednisone, is a synthetic hormone similar to the adrenal hormone hydrocortisone (cortisol). It is sometimes referred to as a corticosteroid or as a cortisteroid. Prednisone is widely used in treatment of chronic conditions involving the immune system. Examples
 are arthritis, asthma, allergic reactions, bronchitis, systemic lupus and leukemias (www.medicinenet.com). 

    Prednisone, available in different registered, prescription brand names (Orasone, Deltasone, Meticorten, Sterapred) (,www.itzarion.com) is a man-made drug that mimics the natural corticosteroids produced in the body. Two functions of prednisone are to act as an anti-inflammatory and as an immunosuppressant (www.chemocare.com, www.itzarion.com). These are the two properties that makes prednisone useful in addressing various chronic diseases. 

    Prednisone must be administered very carefully, and more importantly, stopped very carefully because it causes the adrenal gland to atrophy and cease its natural functioning. Courses of treatment can be short term as for severe asthma or bronchitis, or long term as for lupus or psoriasis. The dose must be regulated, monitored and stopped with the utmost care. When stopping a course of prednisone, the dose must be tapered, slowly reduced by incremants, so that the adrenal glands can reactivate their normal function. Even after a course of prednisone is ended, care must be taken in highly stressful situations (trauma, going to the dentist, respiratory infection, etc.) and an individual may need an extra, short course of prednisone to help through the stressful situation (www.medicinenet.com). 

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Very informative about the use of prednisone. A friend of mine has lupus and takes this and really dislikes taking it. Perhaps someday there will be a drug that gives the same benefits without the terribly high toll on the body

Posted on 08/04/2007 at 3:08:00 PM

Prednisone is evil. It does alleviate symptoms to a great degree... unfortunately, what it is doing behind the scenes is to actually make the condition it is being prescribed for much, much worse. It is being pushed hard in the US because it makes the pharmaceutical companies the big bucks. I quit that crap as soon as I dug a little deeper into it.

Posted on 07/04/2007 at 10:07:00 AM

A nice overview of the side effects of steroids!

Posted on 07/03/2007 at 8:07:00 PM

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