Can an Antibiotic Treat Stroke Victims?

Typically stroke victims need to get to the hospital within three hours of symptoms for clot busting drugs to be effective. This is the optimum time period to establish treatment for the majority of stroke attacks. However, many patients cannot get there within this
 time and there is a need for newer drugs and treatments for the majority that get treatment outside this three hour time frame.

According to new findings in the October 2nd edition of Neurology journal, the antibiotic minocycline could have great results in reducing the damage of a stroke in some patients. Minocycline is a broad spectrum tetracycline antibiotic that is mainly used for acne and other skin conditions. It has some side effects of dizziness and vertigo in some patients that use it, and since it is out of patent it is marketed under a variety of names and brands. The new stroke usage findings show that in a study of 152 stroke patients in Israel that got to the hospital in 6-24 hours after their symptoms began and whose stroke was caused by a blood clot. Such strokes that are from blood clots are called ischemic strokes. They are the most common among stroke victims. 6-24 hours after symptoms is usually too late for some clot busting drugs so half the patients were given minocycline and half weren't. Both groups had routine stroke care. For the patients that were given minocycline there were improvements within a week of the stroke. They believe that the drug works by working on inflammation and curbing cell death. Minocycline cannot help with other stroke issues, so it has no effect on stroke deaths. However, the degree of improvement in a shorter timeframe makes it a viable option for the doctors who are searching for a new way to treat the stroke cases that come in after the three hour window that they like to see.

For more information on strokes

American Heart Association
National Center
7272 Greenville Avenue
Dallas, TX 75231

American Stroke Association
National Center
7272 Greenville Avenue
Dallas TX 75231