Accupril: FDA Approved Therapy for Cardiovascular Complications

Dosing, Side Effects and Contraindications

By Christine Cadena, published Oct 16, 2007
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Cardiovascular complications continue to lead the way in the health care industry, often requiring the use of prescription medications. While there are many prescription drugs on the market designed to improve cardiovascular complications, your physician must choose that which is right for your specific healthcare needs.

As an FDA approved drug, many physician are turning to the ACE inhibitor known as Accupril. With ACE promoting the conversion of angiotensin I, many cardiovascular patients experience vasoconstriction. As a result, the use of an ACE inhibitor will often resolve this complication and restore normal blood pressure levels.

Accupril is available is doses as low as 5 milligrams and as high as 40 milligrams. When used alone, the recommended dosing is that of once-per-day, usually in 10 milligram or 20 milligram doses. When initiating Accupril, to treat hypertension, the drug should be allowed to work on the cardiovascular system for two weeks and then re-evaluation should be made with appropriate dosing adjustments. In very rare cases, dosing of Accupril, to treat hypertension, may need to be increased, including adjustments to twice-per-day dosing recommendations.

As with any FDA approved drug, the use of Accupril, to treat hypertension, does not come without side effects. While most side effects dissipate with treatments, patients with hypertension commonly experience persistent coughing, dizziness, nausea and vomiting and fatigue. When dosing levels are not appropriate, the patient may also experience too low of blood pressure, resulting in the need to adjust the dosing to that of a lower level.

Takeaways
  • Vasoconstriction is common among hypertension patients
  • Accupril is an ACE inhibitor that can reduce vasoconstriction
  • Accupril is not indicated in women who are pregnant
Did You Know?
Patients with pre-existing heart failure or angioedema may not benefit from the use of Accupril.
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